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This choice is informed by the fact that, in AD, the OC is initially affected by A, whereas disease progression leads to subsequent Tau hyperphosphorylation in this brain area

Sakellaris, G., et al

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High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design Acta Crystallogr

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Nursing Considerations Nursing considerations for a patient using H2 antagonists include the following: Nursing Assessment Nursing assessment for a patient using H2 antagonists include: Assess for possible contraindications and cautions: history of allergy to any H2 antagonists to prevent potential allergic reactions