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doi: 10.1016/j.biochi.2020.02.015 98 van HarenMJTaigRKuppensJSastre ToranoJMoretEEParsonsRBet al

Excess levels of histamine change our circadian rhythm and increase our arousal center, so we're just wired awake

Compounding pharmacies and researchers typically use 250 to 500 micrograms per day as an exploratory range, not a clinically proven dose

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