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Some of the key signs of low B12 to look out for include: Muscle weakness Numbness and tingling in the hands and feet Difficulty walking Nausea Weight loss Irritability Fatigue Rapid heart rate (7) One of the other tell-tale symptoms of a B12 deficiency is constant fatigue or being tired all the time, which can also manifest as sleep disturbances, including insomnia in some people, often requiring sleep medications

Mathew, J., Sankar, P., Varacallo, M

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Always consult with a healthcare professional if you have any doubts or questions about your medication

[118] Methionine synthase [edit] Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the MeB 12 and reaction type 2 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine

Your consultation must be completed at least 48 hours before your injection appointment