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Unfolded protein response inhibitors Given the associations mentioned above between the UPR and NF-B, the new functions of UPR inhibitors deserve to be reconsidered

Its central role in buffering intracellular iron and protecting cells from oxidative stress positions it as a potential vulnerability in aggressive brain tumors, such as GBM and MB

This article describes how NRF2 and other transcription factors are targets for protective phytochemicals

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doi:10.1016/j.bbabio.2010.03.006

This discovery suggests that similar underlying pathological processes may be present in both ME/CFS and FM