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Bioinformatics 37 , 24732475 (2021)

Kellis JT, Jr., Vickery LE.Inhibition of human estrogen synthetase (aromatase) by flavones.Science

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Those can include: Renal complications such as kidney stones Blood glucose dysregulation Irritability The issue of insulin resistance and glucose dysregulation is fraught with contradictions in the research, with some papers asserting that exogenous BCAAs could be a cause for insulin resistance and others claiming that genetic predisposition to diabetes and dysfunctional BCAA metabolism exist in parallel but lack a causal relationship