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Estas grandes cantidades de cetones pueden ser txicas para el sistema nervioso y el cerebro, provocando deshidratacin, porque el organismo intenta eliminarla a travs de los riones

Besides altering the acidbase balance, HS also alters electrolyte concentrations, particularly Na + , K + , and Cl , which are crucial for intracellular and extracellular fluid homeostasis (138)

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5.2 Future perspectives and challenges 5.2.1 Ferroptosis-related biomarkers and early diagnosis In the early stages of OA, disturbances in iron homeostasis and increased lipid peroxidation can already be observed in cartilage and synovium