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Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

this results in reduced transcription of mitochondrial ribosomal proteins and mitochondrial transcription factors, and subsequently halting protein translation 101,102

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reliable data could not be obtained at 5-amino-1MQ concentrations above 100 M due to inference with the NAMPT assay readout signal (Figure 4D, Table 3)