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doi: 10.1107/S0907444909047337

The melanoma-associated cancer-testis (CT) antigen (MAGE) is reactivated due to DNA hypomethylation in melanoma and colorectal cancer, which promotes the development of melanoma and colorectal cancer (Kim et al., 2006)

Control cells exhibited a robust SAC, with a median mitotic arrest time of approximately 715 min, whereas BubR1-depleted cells completely lost checkpoint function, exiting mitosis within 20 min (Fig