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Discovery of previously unknown metabolic reactions through isotopologue similarity networking We further developed an isotopologue similarity networking approach, namely IsoNet, by combining mass spectrometry-resolved stable-isotope tracing metabolomics and isotopologue similarity networking between labeled metabolites (Fig

Although serum sampling offers a broader picture of metabolism after TBI and lacks the specificity of cerebral microdialysis approaches, it clearly shows promise as a feasible enhancement to established models of prognostication based on clinical features

Oxidative stress-A key player in the course of alcohol-related liver disease

Figure 2D summarizes the decision framework for selecting blood versus ISF sampling across diverse biomarker classes

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10.1002/acn3.322 Ann