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Treatment may always be useful to correct clinical abnormalities like vitamin B 12 related haematological abnormalities, psychiatric and depressive symptoms

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doi: 10.3390/cells12212555 16 FanRLiuHLiangQ

In contrast, under high-iron conditions, IRPs undergo conformational inactivation and dissociate from IREs, allowing increased synthesis of ferritin and FPN1 and reduced iron uptake (Sanchez et al., 2007

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