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Phosphorylation of IB by the IKK complex triggers its recognition by an E3 ligase complex which leads to its polyubiquitination and subsequent degradation by the proteasome

It exerts an effect on chloride channels that results in reduced granular release of mediators contributing to allergic reactions (as depicted in Figure 11) when mast cells & eosinophils are stimulated by an IgE-allergen complex

Vitamin B-12 also plays a role in the synthesis of neurotransmitters

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Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different sub cellular compartments