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Medicines which can decrease the absorption of Vitamin B12 include: Colchicine (a medicine used to treat gout) Metformin (an anti-diabetic agent) Excessive Alcohol Vitamin C products

Water-testing kits with instructions can be picked up at 13015 Taylor Complex Lane on: Monday, June 10 from 9 a.m.-7 p.m

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References AbdElrahman SH, Saudy HS, Abd ElFattah DA, Hashem FA (2022) Effect of irrigation water and organic fertilizer on reducing nitrate accumulation and boosting lettuce productivity

Disclosures: Richard Morrow: Nothing to Disclose, Dahn Jeong: Nothing to Disclose, Jean Makuza: Nothing to Disclose, Michael Irvine: Nothing to Disclose, Alnoor Ramji: Nothing to Disclose, Hin Hin Ko: Nothing to Disclose, Mel Krajden: Nothing to Disclose, Sofia Bartlett: Nothing to Disclose, Stanley Wong: Nothing to Disclose, Amanda Yu: Nothing to Disclose, JASON WONG: Nothing to Disclose, Julia Li: Nothing to Disclose, Naveed Janjua: Nothing to Disclose 381 HEPATITIS B TREATMENT OUTCOMES AND FACTORS ASSOCIATED WITH HBV TREATMENT SUCCESS: A POPULATION-BASED STUDY IN RWANDA Jean Damascene Makuza 1 Dahn Jeong 2 Atul Aravindakshan 3 Richard Morrow 3 Prince Adu 4 Marie Paul Nisingizwe 3 Georgine Cua 4 Hctor Velsquez Garca 4 Janvier Serumondo 5 Albert Tuyishime 5 Joseph Puyat 3 Joseph Puyat 3 Alnoor Ramji 2 Michael Law 3 Naveed Janjua 4 , 1 The University of British Columbia, SPPH, 2 University of British Columbia, 3 The University of British Columbia, 4 British Columbia Centre for Disease Control, 5 Rwanda Biomedical Centre Background: Timely treatment of chronic hepatitis B virus (HBV) infection reduces complications such as cirrhosis and hepatocellular carcinoma and improves overall survival

36 Those stimuli phosphorylate IB kinase (IKK) complex, 37 and induce degradation of IB, thus releasing NF-B to translocate to nucleus