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[2] Malic enzyme Pyruvate can also be produced from malate

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Genetic insights should support provider-guided dosing decisions, not replace clinical evaluation

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Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors

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A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohns disease

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The hypothesis that deficient serotonergic neurotransmission contributes to the pathogenesis of MDD originated from clinical observations that amine-depleting drugs induced depressive states, whereas monoamine oxidase inhibitors, which prevent the breakdown of serotonin (5-HT), alleviated depressive symptoms [4, 5]

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