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Various topical creams, lotions, and ointments have been made in an attempt to address the negative effects of sun damage on the skin either by prevention or treatment

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Mn toxicity has also been investigated in the lungs, liver, and kidneys

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Recent studies have emphasized the importance of combination therapy, namely, the synergistic action of stem cells and bioactive scaffolds, targeting multifactorial pathological processes (such as oxidative stress, inflammation, ECM degradation, and apoptosis) for comprehensive treatment