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At the level of gene transcription, the fact that three different proteins can be synthesized from gpx4, due to the presence of multiple transcriptional start sites, yielding the mitochondrial (m-), nuclear (n-), and cytosolic (c-) GPx4 forms, makes the issue of gene regulation extremely complex 54

& Hidalgo, A

Part of the PlexusDx Education Hub, this article sits alongside our wider coverage of longevity protocols and the genetics that shape metabolic decisions

The first system is grounded in the neuroscience of brain states and our ability to perform (and to avoid) certain tasks at different phases of the 24-hour day

Goal: Support satiety, reduce food intake, and promote weight management over time [2] [4]

Conflicts of Interest The authors declare that they have no competing interests