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However, further work is still needed to optimise these platforms for commercialisation specifically in relation to their sensitivity, specificity and overall reliability

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Cu enzymes are involved in the oxidation of metals and organic substrates and produce a variety of metabolites, neuropeptides, pigments, and other bioactive compounds (Solomon et al., 2014)

Finally, considering that mitochondria emerged as the most sensitive organelle to Cu toxicity in Wilson disease 13,31 , we investigated the impact of PrP suppression on mitochondrial function