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Dominguez-Martinez M, Caro-Llopis A, Martin-Grau C, Rosello M, Oltra S, Pedrola L, Monfort S, Gabaldon-Albero A, Martinez F, Orellana C

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indicates that PAC, in the absence of adequate, physiological levels of GSH, may give rise to genotoxic quinone imine metabolites (Klopi et al., 2015)

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Although there is ample evidence of fatty acid uptake in tumors in vivo 324,325 fueled by lipolysis of adipocytes contributing to cachexia 326,327 , and sometimes in response to compensate for suppression of fatty acid synthesis 18,328 , evidence supporting -oxidation within solid tumors is less explored 318