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Semaglutide causes nausea through two primary mechanisms involving GLP-1 receptor activation

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As a result, the BBB is a key regulator of microorganism entry into the CNS and exists at the interface of blood vessels and interstitial fluid throughout the brain

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In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose