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Beneath that surface similarity, however, they are genuinely different molecules: BPC-157 is a 15-amino-acid sequence isolated from a cytoprotective fraction of human gastric juice and characterized by Predrag Sikiric and the Zagreb group, while TB-500 is a 17-amino-acid synthetic fragment of the 43-residue actin-sequestering protein Thymosin Beta-4 (T4), originally isolated from calf thymus by Allan Goldstein and colleagues

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doi: 10.1016/0022-3468(92)90356-C 22 RabahHRabahA

Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4