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HepG2, HepaRG, LX-2), primary cell cultures (e.g

In this review, we focus on the sites where mitochondrial biogenesis occurs in neurons and the mechanisms by which it maintains axonal mitochondrial density

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Apc-mutated intestinal tumors lacking Stard7 are sensitive to mTORC1 inhibition Given the fact that intestinal tumors arising from constitutive Wnt signaling and lacking Stard7 show enhanced mTORC1 signaling, we hypothesized that these malignancies would be very sensitive to mTORC1 pharmacological inhibition