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Moreover, although ferroptosis has been thoroughly investigated in relation to MIRI, its connections with other types of cell death, such as apoptosis and necrosis, are still not well understood, especially within the wider context of cardiovascular diseases

The potential metabolic benefits of metformin, attributed to its action in the intestine, have also been highlighted

doi:10.1126/scitranslmed.aaz2841 Mizota T, Hishiki T, Shinoda M, et al

What's remarkable about all eight conditions is that pharmacologic intervention alone is not the answer and neither, for many, is behavior change

8H, I), with no overt toxicity as evidenced by comparable body weights among groups (Supplementary Fig

Declaration of Conflicting Interests The authors report no conflicts of interest in this work