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Feldman HA, Zhou N, Antonoff MB, Hofstetter WL, Rajaram R, Rice DC , Sepesi B, Vaporciyan AA, Zorrilla-Vaca A, Mehran RJ

In this setting as well, treatments with antioxidant substances could be appropriate, but literature data indicate that antioxidants alone are unable to induce significant clinical changes, except perhaps in mild forms, and must be used in conjunction with standard drug treatments to achieve measurable results (124)

And, like, not get up to use the restroom

Combining treatments can target these problems together

HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice