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(So if youve been taking a B complex supplement on that empty stomach as you dash out the door, youre good.) However, in some people, a bunch of B vitamins on an empty stomach can cause mild nausea or a jittery feeling

If you are experiencing hair fall and suspect B12, look for accompanying signs: Neurological: Tingling or numbness in hands and feet Memory issues or brain fog Fatigue and weakness disproportionate to activity level Hematological: Pallor, breathlessness on exertion (from anemia) Rapid heartbeat at rest Oral: Soreness or redness of the tongue (glossitis) Mouth ulcers Skin: Hyperpigmentation (particularly in darker skin tones) Premature graying B12 deficiency is associated with early hair greying as melanin synthesis requires adequate B12 If you have hair loss without any of these symptoms, androgenetic alopecia is a more likely primary diagnosis though B12 can coexist as a contributing factor

Shi Z, Zheng J, Tang W, Bai Y, Zhang L, Xuan Z, Sun H, Shao C

When megaloblastic anemia develops, vascular congestion increases and periorbital hyperpigmentation occurs

doi: 10.1016/j.matbio.2005.09.001 71 WangDSongJMaH

In the present study, this mechanistic interpretation remains provisional, consistent with the planned pairwise comparisons showing no significant between-concentration differences within either phase