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The expression levels of CYP4A1 was significantly increased, 17-HSD2 (17 hydroxyl steroid dehydrogenase type 2) was decreased, and CYP4A2 (cytochrome P450 1A2) not statistically changed in ibuprofen treated male livers (Fig

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Additionally, these stressors can influence epigenetic processes associated with activation of the inflammatory and oxidative stress pathways [22,23,24]

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