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The self-assembled Bacteriphage MS2 VLP, which is modified with SP94 peptide and encapsulated with doxorubicin, cisplatin, and 5-fluoro-uracil to selectively transport and kill human hepatocellular carcinoma (HCC) in the Hep3B cell line, is a classic example of VLPs as targeted therapeutic carriers (147)

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Participants in the trial received weekly Li-ESWT treatments for three weeks, followed by a PRP injection on the same day as the last shockwave treatment