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doi: 10.3389/fphar.2014.00260 Received 09 July 2014 Accepted 08 November 2014 Published 27 November 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Salvatore Salomone, Catania University, Italy

The specific ROS/RNS and corresponding reactions/pathways involved in chronic diseases and associated LUTS should be identified in the future and could serve as therapeutic targets