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In this study we used electrochemistry-based targeted metabolomics to gain insights into the mechanisms of action of escitalopram/citalopram focusing on a set of 31 metabolites from neurotransmitter-related pathways

Cell viability was evaluated by MTT assay

Nevertheless, there are also opposite examples of the effect of Nrf2 knockout on oxidative stress and signs of aging

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doi: 10.1016/j.sjbs.2018.04.008 41 FilipskyT.RihaM.MacakovaK.AnzenbacherovaE.KarlickovaJ.MladenkaP

Moreover, alcohol consumption induces macrophages to produce IL-6 via a PRMT1-dependent mechanism, which activates STAT3 signaling in hepatocytes and drives tumor progression