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Description

Sleeping beauty: quiescence in Saccharomyces cerevisiae

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After inducing ischemic AKI in 810-week-old, male C57BL/6 mice, mass spectrometry metabolomics revealed that the liver had the most distinct phenotype 24 h after AKI versus 4 h and 7 days

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In macrophages, heme is first decomposed to generate biliverdin by heme oxygenase-1 (HO-1), which then undergoes reduction to bilirubin by biliverdin reductase(BVR) (5, 6) ( Figure 1 )

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FIGURE 1 There are several examples of drugs becoming toxic/bioactive following their conjugation with GSH

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doi: 10.3324/haematol.2019.232793

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