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Similar content being viewed by others Sodium aescinate (SA), a triterpene saponin extracted from horse chestnut trees seeds and dried fruits, was first marketed in Germany during the 1970s and has anti-inflammatory, anti-edematous, anti-exudation, vasoprotective, and antioxidant effects 1,2,3

Nat Commun 6 , 6761 (2015)

Judd J, Abdel Karim N, Khan H, et al

Lu : Khng s dng thay th cho ch n ung a dng, cn bng v li sng lnh mnh

Njoku, Chinedu N

Its effects on feeding are well documented, however both pharmacological blockade of central IL-1 or IL-6 signaling, and genetic deficiency of IL-1 receptor or IL-6 receptor have resulted in attenuated food intake and weight loss