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Additional information Peer review information Nature Communications thanks Caryn Outten, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Moreover, studies in mice and humans demonstrated that the effective suppression of neuronal hyperactivity can improve or even restore cognitive function 20,47

First, these hydrogels provide a controlled release of antioxidants, allowing gradual scavenging of excess reactive oxygen species (ROS) to maintain oxidative balance and reduce long-term tissue damage (Valentino et al., 2022)