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1991;18(4 Suppl 1):76-83

Alpha lipoic acid (50mg) is a naturally occurring antioxidant compound involved in energy metabolism

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This process regulates the miR-770-3p/triggering receptor expressed on myeloid cells 2 (TREM2) axis, thereby promoting microglial transition from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype, which alleviates cognitive impairment and neuronal damage in AD mouse models [191]

Yes, the human clinical trial evidence is lacking, but there is a silver lining emerging from years of self-experimentation

Here, we found that Pit-1 overexpression or knockdown in human breast cancer cell lines induced profound phenotypic changes in the expression of proteins involved in cell proliferation, apoptosis, and invasion