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However, another large-scale study, conducted on data from Sweden that included controlling for the genetic background of participants, showed no such association

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Gln deprivation can enhance the sensitivity of A2780cis cells to cisplatin by promoting the methylation of the GS promoter, inhibiting GS synthesis, and downregulating intracellular GSH levels ( Furthermore, Gln metabolism can also exert epigenetic influences on tumor resistance

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10.1016/j.phrs.2022.106505 8 HaoH.XuY.ChenR.QiS.LiuX.LinB.et al (2024)

The mice were distributed in isolated metallic cages of size 15 10 8 under controlled conditions with standard food and water