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Figure 1 2.1 Phenolic acids and flavonoids Phenolic acids differ from other acids in that they contain a single phenolic ring, characterized by the presence of one carboxylic acid group and one or more hydroxyl groups ( They are generally divided into two major subgroups: hydroxybenzoic acids and hydroxycinnamic acids

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Interestingly, while (R)-crizotinib, the clinically used form, is inactive against MTH1, the (S)-enantiomer of crizotinib selectively inhibits MTH1 catalytic activity

Molecules 22 (11), 2029

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