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Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

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Tosic M, Ott J, Barral S, Bovet P, Deppen P, Gheorghita F, et al

Research has shown that alcohol stimulates hepatocytes to release extracellular vesicles containing CD40L in a caspase-3-dependent manner [167], thereby activating macrophages and increasing the production of inflammatory cytokines