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In addition, the essential oil extract of prickly ash has shown promising effects in immune regulation, inflammation regulation, modulation of intestinal flora, and maintenance of intestinal barrier function

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2017;7(7):Cd009881

The activation of the non-canonical NF-B pathway has an important role in the functions of adaptive immunity

Figure: negatively charged phospholipids in biological membranes To study this they used the C2 domain of lactadherin (Lact-C2) from milk that binds PS in the presence of calcium