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Description

Primary injury results directly from external forces and encompasses the disruption of the bloodbrain barrier (BBB), damage to axonal fibers and cellular death [5]

Plants 9(1), 119

This process is mediated by glutaredoxins (GLRXs, also known as GRXs), which catalyze both glutathionylation and deglutathionylation, as well as by sulfiredoxins (SRXs) 9,10

7,9,15 The entire sequence of events is coordinated through copper acting as a catalytic cofactor in its redox chemistry, which entails complex interactions with various intracellular enzymes and proteins