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For samples stained with IHC, tissue samples were counterstained with hematoxylin, dehydrated, and mounted

Figure 1 shows how O 2 - promotes the formation of H 2 O 2 , OH, and ONOO - by various chemical pathways

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Regional enteritis

Mito-TEMPO modulated the mitochondrial functioning and restored mitochondrial membrane potential in 5-FU-induced intestinal injury Since the mitochondrial oxidative stress may have resulted from defective mitochondrial functioning, we were further encouraged to assess activities of respiratory chain enzymes, TCA cycle enzymes and mitochondrial membrane potential in mice intestine