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In addition, the HMGB1-TLR2 signal can upregulate PD-L1 on neutrophils, inducing T cell apoptosis and causing immunosuppression, which may ultimately lead to multiple organ dysfunction (156)

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On the other hand, evidence suggests that a short course of corticosteroids at the onset of the disease may be beneficial in patients with autoimmune hypophysitis after viral infections or vaccinations and may improve the associated immunological alterations (35, 74, 79, 242244)

Atopic disease (allergy, asthma, eczema) is induced when IgE sensitization takes place

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