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Description

In DOX-treated cells and mouse hearts, levels of NLRP3 and related proteins were elevated, and calycosin (CA) ameliorated cardiotoxicity via the NLRP3 pathway (99)

Metallothionein isoforms as double agents - their roles in carcinogenesis, cancer progression and chemoresistance

These combination regimens with synergistic effects on multiple mechanisms hold as promise as important potential strategies for overcoming tumor resistance and increasing therapeutic efficacy