larger fusion tags such as glutathione s-transferase or maltose-binding protein Transglutaminase 2 crosslinks the tag, impeding protein–protein interactions of the fused Plasmids 101: Protein tags
Plasmids 101: Protein tags Bacterial Fusion Protein Selection Proteos Insights Maltose Binding Protein an overview ScienceDirect Topics Glutathione S Transferase (GST) Fusion Based Assays for Studying Protein Protein Interactions Springer Nature Experiments Maltose binding protein Wikipedia MBP vs SUMO vs GST vs Thioredoxin: Choosing the Right Fusion Partner Orbion Blog
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