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developed a HA--cyclodextrin (HA--CD) supramolecular complex for the intrarectal delivery of the therapeutic peptide IGF-1C, combining sustained release capabilities with intrinsic anti-inflammatory effects (Fig

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Esto respalda en cierta medida los hallazgos de varios otros grupos de investigacin que no encontraron efectos para mejorar el sueo del DSIP a concentraciones de 30-160 nmol/kg IP o 6-24 nmol/kg ICV