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the disclosure further relates to a pharmaceutical composition a pharmaceutical composition comprising an antibodydrug conjugate as disclosed herein, in combination with one or more pharmaceutical acceptable excipient, diluent or carrier, optionally comprising other active ingredients, for example anti-cancer drugs or immunotherapeutic drugs such as immune checkpoint inhibitors

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Inhibition of cancerous cell proliferation (395), inducing apoptosis (387), and suppressing cell cycle events are promising strategies in the cornerstone of cancer therapies