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Critical Reviews in Clinical Laboratory Sciences

However, there are several limitations

10.1016/j.jinorgbio.2015.09.003 58 SteinbrennerH.SiesH

Future studies on the role of oxidative stress in the comorbidity of both diseases should further clarify the nature of these processes, identify common mechanisms involved in the course of diseases, and consider the role of antioxidants in the development of therapeutic strategies

The American Journal of Clinical Nutrition states that, Severe glutathione deficiency is a critical mechanism underlying the oxidative stress and oxidant damage associated with human aging

With disruption of the mitochondrial membrane potential, these aggregates do not form, and JC-1 remains in its monomeric form emitting a green fluorescence (Ex497/Em528)