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Biochem Biophys Res Commun 293:6106 Taylor ER, Hurrell F, Shannon RJ, Lin TK, Hirst J, Murphy MP (2003) Reversible glutathionylation of complex I increases mitochondrial superoxide formation

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The activation of the Nrf2 pathway triggers a massive endogenous production of Phase II detoxification enzymes, including Heme Oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase 1 (NQO1)