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We demonstrate that sGC agonists (BAY 41-8543 and BAY 54-6544) are effective in reducing the pulmonary fibrotic outcomes of in vivo deficiency of CYB5R3 in AECIIs

Pathophysiology Summary The common pathologic feature in PD and secondary parkinsonism is striatal dopamine deficiency

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10.1016/j.phymed.2025.156538 14 CaoF.XiangJ.WangY.ChenX.LuX.XuX.et al (2024)

Interestingly, after discontinuing Pycnogenol and placebo intake in the fifth cycle of the study, subjects of the Pycnogenol group reported a continuation of the trend, as their need for analgesics was even more reduced (50% compared to baseline), while women of the placebo group experienced a rapid return to analgesics

VCH, 518-521, 1995