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RobinsonMGraySRWatsonMSKennedyGHillABelchJJFet al

doi: 10.1007/978-1-0716-1979-7_34

Interestingly, apical periodontitis at 14 days (AP14) did not differ statistically when compared to the control (70.7 2.2 vs

and 3) gut epithelial cells (enterocytes) and stromal cells, responsible for detecting invading bacteria through extracellular and intracellular pattern recognition receptors (Toll-like receptors TLRs and NOD-like receptors-NLRs)

(1) Omega-3 PUFAs (EPA/DHA) as core antidepressant components Deep-sea fish (e.g., salmon, mackerel) contain 23 g/100 g of EPA and DHA, which target two key pathways of depression: Inhibiting microglial activation: by inhibiting the NF-B/MAPK p38 signaling pathway and activating the neuronal BDNF-PI3K/AKT pathway, the process achieves a balance in microglial M1/M2 polarization and provides neuroprotection against neuroinflammation (313)

thus, autophagy enhancement may preserve fertility via P4 restoration, while inhibition in malignancies could disrupt progesterone-dependent survival circuits [182]