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* Require JNK activation for cytotoxicity The link between GSTs and the MAP kinase pathway provides a rationale as to why many of the selecting drugs are neither subject to conjugation with GSH, nor substrates for GSTs (Tew, 1994)

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It's particularly relevant for those over 40 when natural levels begin declining significantly

Ren Z, Sun S, Sun R, Cui G, Hong L, Rao B, et al