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1d ranged from a modest 28.7% inhibition at 67 M to robust activity with IC 50 = 2.5 M (Table 1)

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Patients with ACOX1 (p.N237S) exhibit loss of glia, Schwann cells and neurons

Glial cell-derived neurotrophic factor induces enteric neurogenesis and improves colon structure and function in mouse models of Hirschsprung disease

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29,32 The neutral and basic amino acid transporter (RBAT, also designated by SLC3A1 ) is another cystine transporter with possible implications in cancer development