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2021) can improve the transparency and reproducibility of MRS

Subtle associations or exam findings relevant to the previously discussed etiologies can guide the subsequent evaluation

When transcriptionally activated and phosphorylated, PGC-1 regulates a number of down-stream transcription factors such as Tfam, MEF-2, NRF-1, NRF-2, ERR and PPAR, which are involved in the expression of selective enzymes in ETC, fatty acid oxidation, UCP3, and MtDNA replication (354)

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Physiol Genom 34(2):162184 Cheng C-F et al (2008) Profiling motility signal-specific genes in primary human keratinocytes

since this discovery, the relevance of selenium to thyroid health has been widely studied