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showed that hydroxyurea effectively treated atherosclerosis, reduced serum cholesterol levels, modified the gut microbiota at various levels, and affected cholesterol absorption by decreasing Niemann-Pick C1-like 1 in the epithelial cells of small intestines of apolipoprotein E knockout ApoE (-/-) mice fed on a high-fat diet (Yang et al., 2022b)

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Jagic V., Turkovic B., Rotkvic I., Mise S., Zoricic I., et al

Beard JR, Officer A, Carvalho IA, Sadana R, Pot AM, Michel JP, Lloyd-Sherlock P, Epping-Jordan JE, Peeters GM, Mahanani WR, Thiyagarajan JA, Chatterij S (2016) The world report on ageing and health: a policy framework for healthy ageing

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